Dr Alexandra Gilbert

BSc Psychology (2001), MBBS (2006), MRCP (2009)

NIHR Academic Clinical Lecturer in Clinical Oncology

Phone: +44 (0)113 206 7516

Email: a.gilbert@leeds.ac.uk

Alexandra Gilbert is an NIHR-funded academic clinical lecturer in clinical oncology with expertise in health services research using patient reported outcomes (PROs) and technical radiotherapy. Her NIHR-funded doctoral research fellowship evaluated the routine collection of PROs using electronic methods to monitor side effects of pelvic radiotherapy in clinical practice and using PRO data to develop normal tissue complication probability models. She is a co-applicant/collaborator on five national and international funded clinical trials providing expertise on PROs in radiotherapy (PLATO, Star TreC, APHRODITE, CORINTH, eRAPID). She has international involvement with PROs development and use in clinical trials and routine practice as member of the EORTC Quality of life group and elected member of the Project and Module Development Committee. She is also a trainee member of the NCRI anorectal cancer subgroup. She has collaborated both nationally and internationally with experts in health services research, PROs, technical radiotherapy and clinical trials.

Alex joined the Leeds Cancer Centre and Patient Centered Research group in 2010 as a National Institute for Health Research (NIHR) Academic Clinical Fellow; combining her training in clinical oncology with research. During this time she prepared a successful application for funding to NIHR for a PhD into the use of Patient Reported Outcome Measures (PROMs) in monitoring side effects following pelvic radiotherapy, which she completed in 2016. She is currently working as an NIHR-funded academic clinical lecturer working on an Academy of Medical Sciences funded project evaluating toxicity related to pelvic radiotherapy and assessing multiple methods for contouring organs at risk.
Alex completed a BSc in Psychology at University College, London prior to studying medicine at Royal Free and University College Medical School. Previous research as a clinical fellow funded by the National Leadership Council considered the experiences of junior doctors working in the NHS. This was a collaborative medical education and leadership development project working with South Central Strategic Health Authority and Wessex Deanery.
Research Interests
Alex’s research interests include:

  • Measurement of patient reported outcomes (PROs) and quality of life of radiotherapy patients in routine clinical practice
  • Using patient reported outcomes to predict radiotherapy toxicity


Gilbert A, Sebag-Montefiore D, Davidson S, Velikova G. Use of patient-reported outcomes to measure symptoms and health related quality of life in the clinic. Gynecologic oncology. 2015;136(3):429-39.

Gilbert A, Ziegler L, Martland M, Davidson S, Efficace F, Sebag-Montefiore D, et al. Systematic Review of Radiation Therapy Toxicity Reporting in Randomized Controlled Trials of Rectal Cancer: A Comparison of Patient-Reported Outcomes and Clinician Toxicity Reporting. International journal of radiation oncology, biology, physics. 2015;92(3):555-67.

Sodergren SC, Vassiliou V, Dennis K, Tomaszewski KA, Gilbert A, Glynne-Jones R, et al. Systematic review of the quality of life issues associated with anal cancer and its treatment with radiochemotherapy. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2015.

Prestwich R, Teo, M, Gilbert A, Williams G, Dyker K, Sen M. Long term swallow function post-chemoradiotherapy for oropharyngeal cancer: the influence of a prophylactic gastrostomy or reactive nasogastric tube. Clin Oncol (R Coll Radiol). 2014 Feb;26(2):103-9. doi: 10.1016/j.clon.2013.10.005. Epub 2013 Nov 15.

Efficace F, Jacobs M, Pusic A, Greimel E, Piciocchi A, Kieffer JM, Gilbert A, Fayers P, Blazeby J. EORTC Quality of Life Group (Patient Reported Outcome Measurements Over Time In ONcology-PROMOTION Registry). Patient-reported outcomes in randomised controlled trials of gynaecological cancers: Investigating methodological quality and impact on clinical decision-making. Eur J Cancer. 2014 May 10. pii: S0959-8049(14)00590-5. doi: 10.1016/j.ejca.2014.04.005. [Epub ahead of print]

Gilbert, A., Hockey, P., Vaithianathan, R., Curzen, N. & Lees, P. (2012) Perceptions of Junior doctors in the NHS about their training: Results of a regional questionnaire. BMJ Quality and Safety, published online 25 Jan 2012, DOI: 10.1136/bmjqs-2011-000611

Exworthy, M., Hockey, P. & Gilbert, A. (2012) The teacher and the cop: the role of `private space’ in increasingly transparent clinical practice. Journal of Health Services Research & Policy, 17:1; 60-2.

Prestwich, R., Subesinghe, M., Gilbert A., Şen, M. & Scarsbrook, A. Delayed response assessment with FDG-PET-CT following (chemo)radiotherapy for locally advanced head and neck squamous cell carcinoma. Clinical Radiology, 2012.

On-line publication: Systematic review protocol on PROSPERO database, November 2011 (registration number: CRD42011001726). Gilbert, A. & Zeigler, L. Systematic review to evaluate the late adverse effects experienced by patients following radiotherapy or concomitant chemoradiotherapy for rectal cancer.

Jeffery, KJ., Gilbert, A., Burton, S. & Strudwick, A. (2003) Preserved performance in a hippocampal dependent spatial task despite complete place cell remapping. Hippocampus, 13: 175-189



Oral Presentation: British Association of Day Surgery Annual Conference, Glasgow, 2006. Wright, J., Gilbert, A., Barton-Atkinson, K., Kumar, S., Sweetnam, D. & Ingham Clark, C. Reducing inappropriate admissions for knee arthroscopy; benefit of a “default to day surgery”.

Oral Presentation: Radiological Society of North America (RSNA) 97th Scientific Assembly and Annual Meeting, Chicago, November 27  – December 2, 2011. Subesinghe, M., Gilbert, A., Bhatnagar, P.,  Prestwich, R., Sen. M., Chowdhury, F. & Scarsbrook, A.Use of 18F-FDG PET/CT in Delayed Response Assessment for Stage IV Squamous Cell Head and Neck Cancer.

Poster presentation: Canadian Conference on Medical Education, Toronto, May 2011. Gordon, P., Hunt, P., Beaney, S., Calogeras, A., Coles, C., Gilbert, A., Gilbert, J., Lusznat, R. & Osgood, V. Faculty development: The Wessex Way.

Education exhibit: Radiological Society of North America (RSNA) 97th Scientific Assembly and Annual Meeting, Chicago, November 27  – December 2, 2011.  Bhatnagar, P., Subesinghe, M., Prestwich, R., Gilbert, A., Sen. M. & Scarsbrook, A. Functional Imaging for Treatment Planning, Response Assessment, and Adaptive Therapy in Head and Neck Cancer.



Alex has been involved in medical education throughout her career. Alex wsa successfully awarded a funded post as a Medical Education Associate Trainee (Southampton University Hospitals Trust) for the development of a postgraduate course examining systemic aspects of patient care. This course led on to Alex’s National Leadership Council clinical fellow research into junior doctors experiences in the NHS. During her two year training in Wessex, Alex was a faculty member of the successful Tomorrow’s Teachers course.  Tomorrow’s teachers is a peer-led one day teaching course, which involves facilitating both large and small groups of other trainee doctors in developing their teaching skills. Alex has carried on this interest as the trainee representative on Yorkshire Deanery Generic Education Group and with her involvement on the trainee steering group of the Faculty of Medical Leadership and Management group.


Professional Activities

  • Active member of EORTC Quality of Life Group
  • Trainee representative on Yorkshire Deanery Generic Education Group
  • Member of Trainee Steering group of Faculty of Medical Leadership and Management