Dr Trish Holch

Trish Holch

PhD Psychology (2009), BSc (Hons) Applied Psychology (2003), RGN (1993)

Research Fellow

Email: t.holch@leeds.ac.uk

 

Trish joined the Patient Reported Outcomes Group in 2009 and now holds an honorary contract with the University of Leeds. Her background is in Psychology specifically Behavioural Neuroscience. She completed a PhD (2009) from the Institute of Psychological Sciences at the University of Leeds where she explored ‘the inconsistent effects of the neuropeptide PYY3-36 on appetite’. Trish attained a BSc (Hons) degree in Applied Psychology from the same institution (2003) and as a postgraduate she was a keen member of the Biopsychology Research Group. Following her husband’s diagnosis of terminal prostate cancer Trish changed the focus of her career to the psychosocial needs of oncology patients where she has been able to utilize both her psychological knowledge and former clinical experience as a nurse.

She is one of the co-applicants supporting the Radiotherapy strand of the multi-centre National Institute of Health Research (NIHR)-funded eRAPID programme grant (Leeds and Christie Hospital Manchester). Previously she led a work stream in the NIHR-funded development grant (eRAPID) reviewing and developing items suitable for patients to self-report adverse events (AE) and developing patient and clinical toxicity management advice.

 

Research Interests

Trish’s interests include symptom/adverse event/toxicity monitoring and assessment of quality of life (QOL) in cancer patients including the detection and management of emotional distress and sexual dysfunction in routine clinical practice. Initially funded by the NCRI Compass Collaborative she developed guidelines for oncologists to manage emotional distress in clinics and has explored health professionals’ attitudes to the use of antidepressants in clinical care. To facilitate behaviour change in clinicians Trish was involved in a training programme for Doctors to interpret and incorporate patient reported quality of life (QOL) data into routine consultations. More recently she has completed a systematic review to aid the selection of measures to report adverse events in radical prostate patients in the eRAPID radiotherapy project. She has also worked with staff and patients and used the cognitive interview process and consensus methodology (Delphi) to explore and enable the selection and understanding of questionnaire items.

 

Publications

Ghattaure M, Holborn C, Holch P (March 2016) Assessing the information and support needs of radical prostate cancer patients and acceptability of a group based treatment review: A questionnaire and qualitative interview study. In The British Psychosocial Oncology Society’s (BPOS) Annual Conference. Vol. 25. pp 1-22. Cambridge: Psycho-Oncology

Holch P, Holmes M, Rogers Z, Davidson S, Routledge J, Henry A, Franks K, Gilbert A, Velikova G. (March 2016) Seeking consensus from staff and patients on appropriate patient-reported outcome (PRO) items for radical prostate patients in the eRAPID (Electronic patient self-Reporting of Adverse-events: Patient Information and aDvice) project: a Delphi study. . In The British Psychosocial Oncology Society’s (BPOS) Annual Conference Vol. 25. pp 1-22. Cambridge: Psycho-Oncology

Holmes M, Holch P, Rogers Z, Dickinson S, Davidson S, Routledge J, Henry A, Franks K, Gilbert A, Velikova G. (March 2016) Patient and relatives attitudes to the implementation of eRAPID (Electronic patient self-Reporting of Adverse-events: Patient Information and aDvice) during and after pelvic radiotherapy: A qualitative interview study. In The British Psychosocial Oncology Society’s (BPOS) Annual Conference. Vol. 25 pp 1-22. Cambridge: Psycho-Oncology

Rogers Z, Holch P, Holmes M, Davidson S, Routledge J, Henry A, Franks K, Gilbert A, Dickinson S, Velikova G. (March 2016) Healthcare Professional (HCP) attitudes to the implementation of eRAPID (Electronic patient self-Reporting of Adverse-events: Patient Information and aDvice) during and after pelvic radiotherapy: A qualitative interview study. In The British Psychosocial Oncology Society’s (BPOS) Annual Conference Vol. 25. pp 1-22. Cambridge: Psycho-Oncology

Holch, P, Davidson, S, Routledge, J, Henry, A, Franks, K, Gilbert, A, Bamforth, L, Absolom, K & Velikova, G (2015) eRAPID: Electronic self-report and management of adverse-events for radical prostate radiotherapy (RT) patients Radiotherapy and Oncology 115 (Suppl.1) 201-202

Holch P, Henry A, Franks K, Davidson S,Routledge J, Shearsmith L, Gilbert A, Ingleson E, Albutt A, Velikova G Instruments to record acute and late adverse events (AE) associated with radical prostate cancer treatment for remote monitoring in clinical practice:A systematic review of randomised controlled trials (RCT). (Grant Reference Number RP-PG-0611-20008). Psycho-oncology 24 (Suppl.1) 11-12

Warrington L, Absolom K, Holch P, Gibson A, Horne B, Carter R, Bamforth L, Velikova G. (2015) Developing a system for cancer patients to report symptoms and side-effects of treatment online (eRAPID): Patient experiences from a usability study. Psycho-oncology 24 (Suppl.1) 7-8

Albutt KA, Wem L, Copeland L, Gardner PH, Velikova G, Holch P (2015) Individual-Based vs. Group-Based Psychoeducation Sessions for Breast Cancer Survivors Following Radiotherapy (RT): Impact on Health-Related Quality of Life and Self-Efficacy. Psycho-oncology 24 (Suppl.1) 1-2

Absolom, K, Holch, P, Woroncov, B, Wright, EP & Velikova, G (2015) Beyond lip service and box ticking: how effective patient engagement is integral to the development and delivery of patient-reported outcomes. Quality of Life Research 24(5):1077-1085

Holch P, Absolom K, Velikova G (2014) Development and preliminary evaluation of guidelines for emotional distress management in oncology practice. Psycho-Oncology 23 (Suppl. 2): 1-16

Absolom K, Takeuchi E, Holch P, Warrington L, Hector C, Taylor S, Kenyon L, Ingleson E, Velikova G (2014) Using a patient reported outcome measure to detect emotional distress during cancer treatment. Psycho-Oncology 23 (Suppl. 2): 1-16

Coad J, Kelly J, Kaur J, Vaughan K, Finch A, Holch P, Morgan S, Wright D, Smith S & Stark D (2014) The assessment of psychological wellbeing in Teenagers and Young Adults with cancer. Psycho-Oncology 23 (Suppl. 2): 1-16

Holch P, Warrington L, Potrata B, Ziegler L, Absolom K, Hector C, Keding A, Bamforth L, Harley C & Velikova G (2013) Acceptability of an online system for reporting and managing symptomatic adverse events (eRAPID):Patients views Psycho-Oncology 22 (Supp. 1): 1–29

Hector C, Holch P, Warrington L, Morris C, Ziegler L, Absolom K, Keding A, Bamforth L, Harley C, Velikova G. Development of online patient-advice for the self-management of low-level chemotherapy related toxicities (eRAPID): Involvement of patients and staff.

Holch P, Warrington L, Ziegler L, Hector, Keding A, Bamforth L, Harley C, Mitchell S, A, Basch E, & Velikova G. (2012). Asking the right questions to get the right answers: using cognitive interviews to review the acceptability, comprehensiveness and clinical meaningfulness of patient self-report adverse event items in oncology patients. Quality of Life Research, 21, 16

Holch P, Warrington L, Potrata B. & Velikova G (2012). Can patients self-report adverse events and toxicity during cancer treatment? A cognitive interview study of patient reported toxicity items. Psycho-oncology, 21: 1-20

Ziegler L; Harley C; Holch P; Keding A; Bamforth L; Warrington L; Hector C; Basch E; Velikova G. Towards Safer Delivery and Monitoring of Cancer Treatments. Electronic Patient Self-Reporting of Adverse-Events: Patient Information and aDvice (eRAPID). (2012) Psycho-oncology, 21: 15-15

Holch, P, Absolom, K, L, Pini, S, Holch, Hill, K M. Liu, A, Sharpe, M. Richardson, A, Hosker, C & Velikova, G. (2011) Oncology professionals’ views on the use of antidepressants in cancer patients: a qualitative interview study. British Medical Journal Supportive & Palliative Care, 1(3) 301-305

Absolom K, Holch, P. Pini, S. Hill, K. Lui, A. Sharpe, M. Richardson, A. Velikova, G. (2011): The detection and management of emotional distress in cancer patients: the views of health care professionals. Psycho-oncology, 20(6) 601-608

Rodgers, RJ, Holch, P. & Tallett, A. (2010) Behavioural satiety sequence (BSS) separating the wheat from the chaff in the behavioural pharmacology of appetite. Pharmacology Biochemistry and Behavior, 97: 3-14

Holch, P. & Rodgers, R.J. (2006) Comparative effects of PYY3-36, CCK-8S & sibutramine on food intake, feeding behaviour & weight gain in rats. European Neuropsychopharmacology,16 41-42

Boggiano, M. M.Chandler, P. C. Oswald, K. D. Rodgers, R. J.Blundell, J. E. Ishii, Y. Beattie, A. H. Holch, P. Allison, D. B.et al., (2005) PYY3-36 as an anti-obesity drug target. Obesity Reviews. 6(4):307-322

Holch, P and Rodgers, R.J. (2005). Gut-brain mediated anorexia: Is there a role for PYY3-36? Behavioural Pharmacology, 16 (Suppl): S65

Holch, P. & Rodgers, R.J. (2005). “Is prior fasting a necessary prerequisite for PYY3-36 induced anorexia? .” Appetite 45(3): 366.

Tschöp, M. Castañeda, T. R. Joost, H. G. Thöne-Reineke, C.Ortmann, S. Klaus, S.Hagan, M. M. Chandler, P. C. Oswald, K. D. Benoit, S. C. Seeley, R. J. Kinzig, K. P. Moran, T. H. Beck-sickinger, A. G. Koglin, N. Rodgers, R. J. Blundell, J. E. Ishii, Y. Beattie, A. H. Holch, P. Allison, D. B. et al.(2004) Does the gut hormone PYY3-36 decrease food intake in rodents? Nature 40: 650-652

Madill, A. Holch, P (2004). A range of memory possibilities: The challenge of the False Memory Debate for Clinicians and Researchers, Clinical Psychology and Psychotherapy, 11, 299-310

Ishii,Y. Beattie, A, Holch, P & Rodgers, R.J. (2003). Putative gut hormone PYY3-36 fails to suppress food intake or body weight, Journal of Psychopharmacology, 17 (Suppl): A75

Presentations

2015

Holch, P, Davidson, S, Routledge, J, Henry, A, Franks, K, Gilbert, A, Bamforth, L, Absolom, K & Velikova, G (2015) eRAPID: Electronic self-report and management of adverse-events for radical prostate radiotherapy (RT) patients. ESTRO annual conference Barcelona April 2015 (oral presentation)

Holch P, Henry A, Franks K, Davidson S,Routledge J, Shearsmith L, Gilbert A, Ingleson E, Albutt A, Velikova G Instruments to record acute and late adverse events (AE) associated with radical prostate cancer treatment for remote monitoring in clinical practice:A systematic review of randomised controlled trials (RCT). (Grant Reference Number RP-PG-0611-20008). BPOS annual conference Leeds March 2015 (Poster presentation)

2014

Holch P, Henry A, Franks K, Davidson S,Routledge J, Shearsmith L, Gilbert A, Ingleson, E, Albutt A, Velikova G Instruments to record acute and late adverse events (AE) associated with radical prostate cancer treatment for remote monitoring in clinical practice:A systematic review of randomised controlled trials (RCT). NCRI annual conference Liverpool November 2014 (poster presentation)

Holch P, Absolom K, Velikova G (2014) Development and preliminary evaluation of guidelines for emotional distress management in oncology practice. BPOS Annual Conference Preston Feb 2014 (poster presentation)

Coad J, Kelly J, Kaur J, Vaughan K, Finch A, Holch P, Morgan S, Wright D, Smith S & Stark D (2014) The assessment of psychological wellbeing in Teenagers and Young Adults with cancer. BPOS Annual Conference Preston Feb 2014 (oral presentation)

2013

Holch P, Warrington L, Potrata B, Ziegler L, Absolom K, Hector C, Keding A, Bamforth L, Harley C & Velikova G (2013) Acceptability of an online system for reporting and managing symptomatic adverse events (eRAPID):Patients views. Poster presentation, BPOS Annual Conference, Southampton, January 2013 (winner best poster)

2012

Holch, P, Warrington, L, Ziegler, L, Hector, Keding, A, Bamforth, L, Harley, C, Mitchell, S, A, Basch, E, & Velikova, G. (2012). Asking the right questions to get the right answers: using cognitive interviews to review the acceptability, comprehensiveness and clinical meaningfulness of patient self-report adverse event items in oncology patients. ISOQOL Annual Conference. Budapest, October 2012 (oral presentation)

2011

Holch, P. & Velikova, G. Bridging the gap: Development of guidelines for oncologists to manage emotional distress in cancer patients. Compass Collaborative final annual scientific meeting: Edinburgh April.(Oral presentation)

Holch, P. Do antidepressants have a place in the management of emotional distress in cancer patients? Views of oncology professionals. Research in progress seminar Institute of Molecular Medicine: University of Leeds June (Oral presentation)

Holch P, Absolom, K, K. Hill, K. Pini, S. Lui, A. Sharpe, M. Richardson, A. & Velikova, G. Do antidepressants have a place in the management of emotional distress in cancer patients? views of oncology professionals. Compass Collaborative final annual scientific meeting: Edinburgh April. (Poster presentation)

2010

Holch P, Absolom, K, K. Hill, K. Pini, S. Lui, A. Sharpe, M. Richardson, A. & Velikova, G. Do antidepressants have a place in the management of emotional distress in cancer patients? views of oncology professionals. British Psychosocial Oncology Society: Chester UK. (Poster presentation)

Holch P, Velikova, G. Bridging the gap: Development of guidelines for oncologists to manage emotional distress in cancer patients : Chester UK. (Poster presentation)

 

Teaching

Guest lecturer on the MSc Psychological Approaches to Health (PATH) course IPS University of Leeds (2013 & 2014)

Tutor on the Research, Evaluation and Special Studies module of the year 1 MBChB course.

Trish has completed the University of Leeds Teaching Award (Level 1) in 2010

 

Student supervision

Joint supervision of MSc PATH (Psychological Approaches to Health) student Abigail Albutt ‘Individual-Based vs. Group-Based Psychoeducation Sessions for Breast Cancer Survivors Following Radiotherapy (RT): Impact on Health-Related Quality of Life and Self-Efficacy’ with Dr Pete Gardner IPS University of Leeds (2014)- distinction gained. Oral presentation at BPOS and BPOS student bursary

Joint supervision of Munisha Ghattaure (Radiotherapy practitioner) with Catherine Holborn ‘To identify and assess the needs of radical prostate cancer patients with a view to stratify for a group review’ Sheffield Hallam University MSc Radiotherapy and Oncology (ongoing)-

Joint supervision of Alan Needham (Senior Radiotherapy practitioner) with Dr David Owens LIHS University of Leeds ‘Barriers to referral for sexual function support for patients undergoing prostate radiotherapy’(ongoing)

 

Professional Activities

Secretary of the British Psychosocial Oncology Society (BPOS)

Scientific committee member (BPOS 2014, ISOQOL 2013)

Task force member: ISOQOL Best Practices for PROs in Randomized Clinical Trials

Athena Swan local assessment group member

 

Membership:

International Society for Quality of Life (ISOQOL)

Associate of the Higher Education Academy (HEA)

British Psychosocial Oncology Society (BPOS)

British Psychological Society (BPS)

BPS Division of Health Psychology

BPS Oncology and Palliative care faculty (SiGOPAC)